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5′-三磷酸虫草素 钠盐
Cordycepin 5′-triphosphate sodium salt
产品别名
71997-32-5
5′-三磷酸虫草素 钠盐
Cordycepin 5′-triphosphate sodium salt
3′-Deoxyadenosine 5′-triphosphate
3′-deoxy-ATP
3′-dATP
3′-脱氧腺苷-5′-三磷酸
3′-脱氧-ATP
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H16N5O12P3 |
| Molecular weight | 491.18 |
| MDL number | MFCD00057015 |
| PubChem Substance ID【PubChem化学物质编号】 | 24893135 |
| NACRES | NA.51 |
| General description【一般描述】 | Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin. |
| Application【应用】 | Cordycepin 5′-triphosphate sodium salt has been used:
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| Biochem/physiol Actions【生化/生理作用】 | Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis. 虫草素 5′-三磷酸盐通过 poly (A) 聚合酶掺入核酸中。因为它缺少一个 3′-羟基链的产生，它可用于 3′-RNA 的末端标记。 |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥95% |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)CC3O |
| InChI | 1S/C10H16N5O12P3.Na.H/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(16)1-5(25-10)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-6,10,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);; |
| InChI key | FRGBONDYLMUOMH-UHFFFAOYSA-N |
| packaging【包装】 | 1, 5 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 + H332 - H315 - H319 - H335 - H351 |
| Precautionary Statements | P202 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
