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4-(氯甲基)吡啶盐酸盐
4-(Chloromethyl)pyridine Hydrochloride
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3037964 | 5g | 460 | |||
3037964 | 25g | 1620 | |||
3037964 | 100g | 4990 |
产品别名
1822-51-1
4-(氯甲基)吡啶盐酸盐
4-(Chloromethyl)pyridine Hydrochloride
4-Picolyl Chloride Hydrochloride
基本信息
应用 | It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar 'handle' which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis. It is also applied in conjunction with Amberlyst??15 resin in peptide synthesis. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. |
备注 | Hygroscopic. Store away from oxidizing agents and bases. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. |
MDL | MFCD00012826 |
EINECS | 217-350-7 |
分子式 | C6H62N?HCl |
分子量 | 164.04 |
熔点 | 166-171° |
灵敏度 | Hygroscopic. Ambient temperatures. |
形态 | Crystalline powder |
溶解性 | Soluble in water (750 mg/ml at 20°C), soluble in 1N HCl (2.5%), DMSO, and methanol. |
Beilstein | 3689154 |
包装组 | III |
危险类别 | 21/22-34-43 Harmful in contact with skin and if swallowed.Causes burns.May cause sensitization by skin contact. |
安全信息
危险等级 | 8 |
安全等级 | 24-26-36/37/39-45 Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
欧盟危险品标志 | |
TSCA | 否 |
GHS危害和防范说明
GHS符号 | |
Hazard Statements | H301-H311-H314-H318-H317 Toxic if swallowed.Toxic in contact with skin.Causes severe skin burns and eye damage.Causes serious eye damage.May cause an allergic skin reaction. |
Precautionary Statements | P260h-P301+P310a-P303+P361+P353-P305+P351+P338-P405-P501a IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations. |