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SILuTMProt ALB Albumin human
产品编号: | 4169087 |
规格: | recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
SILuTMProt ALB Albumin human
albumin
基本信息
NACRES | NA.12 |
General description【一般描述】 | SILu™Prot ALB is a recombinant, stable isotope-labeled human albumin which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of albumin in mass-spectrometry. SILu™Prot ALB is a monomer of 607 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~69 kDa. |
Biochem/physiol Actions【生化/生理作用】 | Albumin is synthesized exclusively by the liver parenchymal cells at a rate of 14 g/day. While it is the most abundant plasma protein (>50%), increased urine albumin concentrations indicate bleedings in the lower urinary tract (ureter, bladder) or infections of the renal pelvis. A small abnormal albumin excretion is known as Microalbuminuria and serves as an indicator for temporary overload of the glomerular filtration (fever, excessive sports) or chronic injury of the glomeruli (diabetes). |
Sequence【序列】 | RRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLDYKDDDDKGHHHHHHHHGGQ |
Physical form【外形】 | Supplied as a lyophilized powder containing phosphate buffered saline. |
Legal Information【法律信息】 | SILu is a trademark of sigma-aldrich Co. LLC |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | human |
recombinant【重组】 | expressed in HEK 293 cells |
tag【标签】 | His tagged |
Assay【测定】 | ≥98% (SDS-PAGE) |
form【形式】 | lyophilized powder |
potency【效能】 | ≥98% Heavy amino acids incorporation efficiency by MS |
technique(s) | mass spectrometry (MS): suitable |
suitability【适用性】 | suitable for mass spectrometry (standard) |
UniProt accession no.【UniProt登记号】 | P02768 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ALB(213) |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 2 |