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PKR Inhibitor, Negative Control-CAS 852547-30-9-Calbiochem
| 产品编号： | 4168445 |
| 规格： | The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
| CAS NO： | 852547-30-9 |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
852547-30-9
PKR Inhibitor, Negative Control-CAS 852547-30-9-Calbiochem
RNA-Dependent Protein Kinase Inhibitor, Negative Control, 5-Chloro-3-(3,5-dichloro-4-hydroxybenzylidene)-1,3-dihydro-indol-2-one
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H8Cl3NO2 |
| Molecular weight | 340.59 |
| General description【一般描述】 | An oxindole compound that serves as a negative control for PKR Inhibitor (Cat. No. 527450). Shown to be inactive in inhibiting RNA-induced PKR autophosphorylation (IC50 >100 µM) or in rescuing PKR-dependent translation block. An oxindole compound that serves as a negative control for PKR Inhibitor (Cat. No. 527450). Shown to be inactive in the inhibition of RNA-induced PKR autophosphorylation (IC50 >100 µM). Exhibits no ability to rescue the translational block imposed by human PKR. |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Cell permeable: no Primary Target A negative control for PKR Inhibitor |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Jammi, N.V., et al. 2003. Biochem. Biophys. Res. Commun.308, 50. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (sum of two isomers, HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: 10 mg/mL ethanol: 10 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 10 mg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
