Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide)

HO(C₃H₄O₂)_m(C₂H₄O)_nC₂H₃O₂

Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

powder or chunks

PDLA average M_n 16,000 (by NMR)
PEG average M_n 5,000 (by NMR)

white to tan

−20℃

11 - Combustible Solids

WGK 3