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(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone
产品别名
1208395-99-6
(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone
Probe building block
Hydroxyl benzophenone alkyne
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H12O3 |
| Molecular weight | 252.26 |
| MDL number | MFCD28124082 |
| Application【应用】 | (4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. |
| Other Notes【其他说明】 | Technology Spotlight: Trifuctional Probe Building Blocks A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | solid |
| reaction suitability | reaction type: click chemistry |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
