Safinamide Mesylate

C₁₇H₁₉FN₂O₂ · xCH₄O₃S

302.34 (free base basis)

MFCD15145475

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, safinamide is voltage-dependent sodium and calcium channel blocker. It appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC4350 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

certified reference material
pharmaceutical secondary standard

powder

current certificate can be downloaded

pkg of 50 mg

2-8℃

CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2cccc(F)c2)cc1)C(N)=O

1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1

YKOCHIUQOBQIAC-YDALLXLXSA-N

human ... MAOB(4129)

GHS07,GHS08

Warning

H302 - H319 - H361d

P202 - P264 - P270 - P301 + P312 - P305 + P351 + P338 - P308 + P313

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

11 - Combustible Solids

WGK 3