您的位置：首页 > 产品中心 > 878672-00-5， Lesinurad
Lesinurad
产品别名
878672-00-5
Lesinurad
RDEA 594
2-[[5-Bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H14BrN3O2S |
| Molecular weight | 404.28 |
| MDL number | MFCD22572730 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825493 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorption from the renal tubular lumen. Lesinurad thus reduces serum uric acid levels. Lesinurad has been approved for use in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 25 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | BrC1=NN=C(SCC(O)=O)N1C2=C3C(C=CC=C3)=C(C4CC4)C=C2 |
| InChI | 1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23) |
| InChI key | FGQFOYHRJSUHMR-UHFFFAOYSA-N |
| Gene Information | human ... SLC22A12(116085) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
