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Anti-SLC38A3 Antibody, clone 1A10.2
产品别名
Anti-SLC38A3 Antibody, clone 1A10.2
Sodium-coupled neutral amino acid transporter 3, N-system amino acid transporter 1, Na(+)-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, System N amino acid transporter 1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | The sodium-coupled neutral amino acid transporter 3 (SLC38A3) protein is a sodium-dependent amino acid/proton exchanger (also called an antiporter or counter transporter) SLC38A3 mediates the electrogenic cotransport of glutamine and sodium ions in exchange for protons. SLC38A3 can also transport the amino acids histidine, asparagine and alanine in place of protons. Some evidence exists that SLC38A3 may mediate amino acid transport in either direction under particular physiological conditions such as homeostatic stress like that seen in acidosis, and SLC38A3 plays a role in nitrogen metabolism and synaptic transmission by regulating the levels of sodium and the stimulatory amino acid glutamine. SLC38A3 is localized to the cell membrane and is widely expressed in many tissues, including heart, liver, brain, and prostate. |
Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human SLC38A3. |
Application【应用】 | Research Category Neuroscience Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SLC38A3 in human kidney tissue. Research Sub Category Developmental Signaling Anti-SLC38A3 Antibody, clone 1A10.2 | MABN316 is an antibody against SLC38A3 Antibody for use in Western Blotting, Immunohistochemistry. |
Quality【质量】 | Evaluated by Western Blotting in human kidney tissue lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected SLC38A3 in 10 µg of human kidney tissue lysate. |
Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | 1A10.2, monoclonal |
species reactivity | human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG2aκ |
NCBI accession no.【NCBI登记号】 | NP_006832 |
UniProt accession no.【UniProt登记号】 | Q99624 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~60 kDa observed |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |