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Anti-SIPA1L1 Antibody
产品编号: | 4114313 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-SIPA1L1 Antibody
Signal-induced proliferation associated-like protein 1, SIPA1-like protein 1, E6TP1, High-risk human papilloma viruses E6 oncoproteins targeted protein 1, E6-targeted protein 1, SIPA1L1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Signal-induced proliferation associated-like protein 1 (SIPA1L1), also called High-risk human papilloma viruses E6 oncoproteins targeted protein 1 (E6-targeted protein 1) is widely expressed and bound at the carboxy-terminus by Casein kinase I epsilon (CKIe) which leads to phosphorylation. SIPA1L1 activates RAP2A GTPase activity, aids reorganization of the actin cytoskeleton, recruits DLG4 to F-actin, regulates dendritic spine morphogenesis, and plays important roles in embryo development and cell proliferation. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human SIPA1L1. |
Application【应用】 | Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected SIPA1L1 in human brain tissue. Anti-SIPA1L1 Antibody is a highly specific rabbit polyclonal antibody, that targets Signal-induced proliferation associated-like protein 1 & has been tested in western blotting & IHC. |
Quality【质量】 | Evaluated by Western Blotting in rat brain tissue lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected SIPA1L1 in 15µg of rat brain tissue lysate. |
Other Notes【其他说明】 | Antigen Affinity Purified |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt accession no.【UniProt登记号】 | O43166 |
shipped in【运输】 | wet ice |
Gene Information | human ... SIPA1L1(26037) |
产品说明
Target description【目标描述】 | ~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~198 kDa and ~200 kDa |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |