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Anti-SELK Antibody
产品编号: | 4114109 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-SELK Antibody
Selenoprotein K, HSPC030, HSPC297
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Selenoprotein K (SELK) is a selenoprotein that is localized at the endoplasmic reticulum, and highly expressed in the heart. SELK functions as an antioxidant that can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex. SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins, is thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human SELK. |
Application【应用】 | Anti-SELK Antibody is a highly specific rabbit polyclonal antibody, that targets Selenoprotein K & has been tested in western blotting. Research Category Neuroscience Research Sub Category Developmental Neuroscience |
Quality【质量】 | Evaluated by Western Blotting in A20 cell lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected SELK in 15 µg of A20 cell lysate. |
Physical form【外形】 | Purified rabbit polyclonal PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
Analysis Note【分析说明】 | Control A20 cell lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse |
species reactivity (predicted by homology) | human (immunogen homology) |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | Q9Y6D0 |
shipped in【运输】 | wet ice |
Gene Information | human ... SELK(58515) |
产品说明
Target description【目标描述】 | ~10 kDa observed. Uncharacterized bands may appear in some lysate(s). |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |