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Anti-RCAN1 (N-terminal) antibody produced in rabbit
产品别名
Anti-RCAN1 (N-terminal) antibody produced in rabbit
DSC1
ADAPT78
CSP1
MCIP1
DSCR1
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 28 kDa |
species reactivity (predicted by homology) | mouse, rat, human, canine |
concentration【浓度】 | 0.5 mg/mL |
technique(s) | western blot: 1 μg/mL |
NCBI accession no.【NCBI登记号】 | NM_004414 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RCAN1(57396) |
基本信息
General description【一般描述】 | RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. |
Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human RCAN1 |
Sequence【序列】 | Synthetic peptide located within the following region: MEDGVAGPQLGAAAEAAEAAEARARPGVTLRPFAPLSGAAEADEGGGDWS |
Physical form【外形】 | Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | nwg |