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Anti-Pinch-1 Antibody, clone 9D2.1
产品别名
Anti-Pinch-1 Antibody, clone 9D2.1
LIM and senescent cell antigen-like-containing domain protein 1, Particularly interesting new Cys-His protein 1, PINCH-1, Renal carcinoma antigen NY-REN-48
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Pinch-1 (Particularly interesting new Cys-His protein 1) is also known as LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1). Pinch-1 is expressed in most tissues except for brain. Pinch-1 is an adhesion protein and is part of the ILK-PINCH complex that is involved in integrin and growth factor signaling by coupling surface receptors to downstream signaling molecules related to the regulation of cell survival, cell proliferation and cell differentiation. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Pinch-1. |
| Application【应用】 | Research Category Cell Structure Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Pinch-1 in human renal tubules and mouse renal tubules tissue. Research Sub Category Adhesion (CAMs) Anti-Pinch-1 Antibody, clone 9D2.1 is a highly specific mouse monoclonal antibody, that targets Pinch-1 & has been tested in western blotting & IHC. |
| Quality【质量】 | Evaluated by Western Blotting in human heart tissue lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pinch-1 in 10 µg of human heart tissue lysate. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Format: Purified Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Human heart tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 9D2.1, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgMκ |
| NCBI accession no.【NCBI登记号】 | NP_001180411 |
| UniProt accession no.【UniProt登记号】 | P48059 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~40 kDa observed. Uniprot describes 4 isoforms produced by alternative splicing at ~38 kDa, ~44 kDa, ~37 kDa, and ~42 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
