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Anti-Phospho-p53-S46 antibody produced in rabbit

产品编号:4112539
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4112539100 μL4710
产品别名

Anti-Phospho-p53-S46 antibody produced in rabbit

BCC7

TP53

BMFS5

TRP53

LFS1

P53

产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
23-43
species reactivity
human
concentration【浓度】
0.33 mg/ml
technique(s)
immunoprecipitation (IP): 1:50-1:100
western blot: 1:1000-1:2000
UniProt accession no.【UniProt登记号】
P04637
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... TP53(7157)
基本信息
General description【一般描述】
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
Immunogen【免疫原】
A synthetic phosphorylated peptide around S46 of human p53 (NP_000537.3).
Physical form【外形】
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品说明
Storage and Stability【储存及稳定性】
Store at -20℃. Avoid freeze / thaw cycles.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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