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Anti-CD73 Antibody, clone AA60-E3-3
产品别名
Anti-CD73 Antibody, clone AA60-E3-3
5′-nucleotidase, 5′-NT, ecto-5′-nucleotidase
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | CD73, also known as Ecto-5′-nucleotidase, catalyzes the conversion of purine 5′ mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation, being expressed on subsets of B-cells and T-cells. CD73 is also a marker of undifferentiated mesenchymal stem cells and is often used to identified stem cell populations. |
| Immunogen【免疫原】 | Whole Mouse Dermal Lymphatic Endothelial Cells (DLEC) |
| Application【应用】 | Detect CD73 using this mouse monoclonal antibody, Anti-CD73 Antibody, clone AA60-E3-3 validated for use in ICC, Flow Cytometry, western blotting & IP. Research Sub Category Mesenchymal Stem Cells This antibody has been shown to work in immunocytochemical applications on human adipose mesenchymal stem cells. This antibody has been shown to work in western blot applications on HMEC-1 cells by an independant lab.This antibody has been shown to work in immunoprecipitation applications on HMEC-1 cells by an independant lab. Research Category Stem Cell Research |
| Quality【质量】 | Evaluated by Flow Cytometry on human adipose mesenchymal stem cells. Flow Cytometry Analysis: 1 µg/mL of this antibody detected CD73 on 1X10^6 human adipose mesenchymal stem cells. |
| Linkage【联系】 | Replaces: MABC668 |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control Human Adipose Mesenchymal Stem Cells |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | AA60-E3-3, monoclonal |
| species reactivity | human |
| species reactivity (predicted by homology) | mouse (immunogen homology) |
| technique(s) | flow cytometry: suitable immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001191742 |
| UniProt accession no.【UniProt登记号】 | P21589 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 63 kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
