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产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | liquid |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | 2.4 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 | P42081 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CD86(942) |
基本信息
| General description【一般描述】 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
| Immunogen【免疫原】 | Recombinant protein of human CD86. |
| Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
