广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-Mitofusin-1 Antibody
产品搜索:

Anti-Mitofusin-1 Antibody

产品编号:4094515
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4094515100 μG6020
产品别名

Anti-Mitofusin-1 Antibody

Fzo homolog, Transmembrane GTPase MFN1, Mitofusion-1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Along with Mitofusin-2 (Mfn2), Mitofusin-1 (Mfn1) is a known protein mediator of mitochondrial fusion. Mitochondrial fusion regulates mitochondrial morphogensis and supports complementation between mitochondrial genomes in mammalian cells. Two Mfn1 transcripts are detected at similar levels in a variety of human tissues and are dramatically elevated in the heart. Human Mfn1 is known to be localized in the mitochondria. It is reported that point mutations in the conserved G1 and G2 region of the Mfn1 GTPase domain result in decreased formation and fragmentation of the mitochondria, respectively.
Specificity【特异性】
This antibody recognizes Mitofusin-1 at the cytoplasmic domain.
Immunogen【免疫原】
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Mitofusin-1.
Epitope: Cytoplasmic Domain
Application【应用】
Research Category
Cell Structure
Detect Mitofusin-1 using this Anti-Mitofusin-1 Antibody validated for use in WB.
Research Sub Category
Organelle & Cell Markers
Quality【质量】
Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Mitofusin-1 in 10 µg HeLa cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
Analysis Note【分析说明】
Control
HeLa cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
rat, mouse, human
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_284941
UniProt accession no.【UniProt登记号】
Q8IWA4
产品说明
Target description【目标描述】
~86 kDa observed.
Three isoforms of Mitofusin-1 are produced by alternative splicing with molecular weights of ~42 kDa, ~71 kDa, and ~84 kDa Uncharacterized bands may appear at ~45 kDa, ~48 kDa, and ~55 kDa in some lysates.
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0102