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白细胞介素-2 人
Interleukin-2 human
| 产品编号： | 4094028 |
| 规格： | recombinant, expressed in Pichia pastoris, suitable for cell culture |
| 包装规格： | 10000 UNITS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
白细胞介素-2 人
Interleukin-2 human
T-cell growth factor
Interleukin-2
IL-2
白细胞介素-2
T细胞生长因子
基本信息
| MDL number | MFCD00165721 |
| NACRES | NA.75 |
| Application【应用】 | Interleukin-2 human has been used to assess changes in tumor necrosis factor receptor 1 (TNFR1). It has also been used in TNFR2 expression on Tregs. |
| Biochem/physiol Actions【生化/生理作用】 | Interleukin 2 (IL2) is a pro-inflammatory cytokine. It consists of three subunits, in which the β subunit is important for receptor mediated signaling. IL2 enhances the development of T regulatory cells and plays a crucial role in antitumor immunity. 白细胞介素-2(IL-2)是由某些T淋巴细胞亚群产生的免疫调节因子。该淋巴因子能够促进活化T细胞和相关细胞类型的长期生长。IL-2在NK细胞的激活和增殖、诱导γ-干扰素和B细胞生长因子分泌中发挥作用，并且能够调节IL-2受体的表达。 |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in 50 mM sodium phosphate buffer, pH 7.0, containing 0.1% human serum albumin per 0.1 mL of cytokine. |
| Analysis Note【分析说明】 | The biological activity is tested in a cell proliferation assay using an IL-2 dependent murine cytotoxic T cell line, CTLL-2. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in Pichia pastoris |
| Assay【测定】 | ≥98% (SDS-PAGE and HPLC) |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | predicted mol wt ~15 kDa |
| packaging【包装】 | pkg of 10KU |
| technique(s) | cell culture | mammalian: suitable |
| impurities【杂质】 | endotoxin, tested |
| web metadata keyword.default | TCGF |
| UniProt accession no.【UniProt登记号】 | P60568 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL2(3558) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
