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Histone H3.1 human
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4093840 | 100 μG | 1250 |
产品别名
1523001-32-2
Histone H3.1 human
Histone, Human
基本信息
NACRES | NA.25 |
General description【一般描述】 | Histone H3.1 is a histone H3 variant. It differs from H3.2 with residue 96 being a cysteine instead of serine. H3.1 is a replication-dependent histone and is a component of nucleosomes during the S-phase. |
Application【应用】 | Histone H3.1 human has been used in in vitro Schizosaccharomyces pombe Set7 histone methyltransferase assay for matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) studies. |
Biochem/physiol Actions【生化/生理作用】 | Histone H3.1 human (H3.1) undergoes a majority of post-translational modification especially acetylation and demethylation in lysine 14 and 9 respectively. During differentiation, the levels of H3.1 transcripts decrease as cell division slows down. The incorporation of H3.1 into chromatin is mediated by a chaperone, chromatin assembly factor (CAF-1). A transversion mutation in the H3.1 may be implicated in glioma. |
Physical form【外形】 | Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA, and 1 mM DTT. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | human |
recombinant【重组】 | expressed in E. coli |
form【形式】 | liquid |
concentration【浓度】 | 1 mg/mL |
technique(s) | MALDI-TOF: suitable |
UniProt accession no.【UniProt登记号】 | P68431 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... H3C1(8350) |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H319 |
Precautionary Statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
Hazard Classifications【危险分类】 | Eye Irrit. 2 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |