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Histone H3.1 human

产品编号:4093840
CAS NO:1523001-32-2
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4093840100 μG1250
产品别名

1523001-32-2

Histone H3.1 human

Histone, Human

基本信息
NACRES
NA.25
General description【一般描述】
Histone H3.1 is a histone H3 variant. It differs from H3.2 with residue 96 being a cysteine instead of serine. H3.1 is a replication-dependent histone and is a component of nucleosomes during the S-phase.
Application【应用】
Histone H3.1 human has been used in in vitro Schizosaccharomyces pombe Set7 histone methyltransferase assay for matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) studies.
Biochem/physiol Actions【生化/生理作用】
Histone H3.1 human (H3.1) undergoes a majority of post-translational modification especially acetylation and demethylation in lysine 14 and 9 respectively. During differentiation, the levels of H3.1 transcripts decrease as cell division slows down. The incorporation of H3.1 into chromatin is mediated by a chaperone, chromatin assembly factor (CAF-1). A transversion mutation in the H3.1 may be implicated in glioma.
Physical form【外形】
Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA, and 1 mM DTT.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
human
recombinant【重组】
expressed in E. coli
form【形式】
liquid
concentration【浓度】
1 mg/mL
technique(s)
MALDI-TOF: suitable
UniProt accession no.【UniProt登记号】
P68431
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... H3C1(8350)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H319
Precautionary Statements
P264 - P280 - P305 + P351 + P338 - P337 + P313
Hazard Classifications【危险分类】
Eye Irrit. 2
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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