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氟胞嘧啶
Flucytosine
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4093131 | 1 G | 1600 |
产品别名
2022-85-7
氟胞嘧啶
Flucytosine
4-amino-5-fluoro-2(1H)-pyrimidinone
5-Fluorocytosine
4-氨基-5-氟-2(1H)-嘧啶酮
5-氟胞嘧啶
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C4H4FN3O |
Molecular weight | 129.09 |
Beilstein | 127285 |
EC number【EC 号】 | 217-968-7 |
MDL number | MFCD00006035 |
PubChem Substance ID【PubChem化学物质编号】 | 329823537 |
General description【一般描述】 | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Flucytosine is an antimycotic drug that can be effectively utilized against severe Candida and Cryptococcus infections. |
Application【应用】 | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Flucytosine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques. |
Biochem/physiol Actions【生化/生理作用】 | 具有抗真菌活性的核苷类似物。5-氟胞嘧啶通过胞嘧啶脱氨酶脱氨,得到 5-氟尿嘧啶,从而导致 RNA 错编。5-氟胞嘧啶抑制 DNA 和 RNA 的合成并干扰核糖体蛋白的合成。 |
Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAA5760 in the slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
Quality Level【质量水平】 | 300 |
grade【等级】 | certified reference material pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
packaging【包装】 | pkg of 1 g |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
mp | 298-300 ℃ (dec.) (lit.) |
application(s) | pharmaceutical (small molecule) |
format【格式】 | neat |
pharmacopeia traceability【药典可追溯性】 | traceable to PhEur F0175000 traceable to USP 1272000 |
storage temp.【储存温度】 | 2-30℃ |
SMILES string | NC1=NC(=O)NC=C1F |
InChI | 1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9) |
InChI key | XRECTZIEBJDKEO-UHFFFAOYSA-N |
安全信息
Pictograms【象形图】 | GHS08 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H361 |
Precautionary Statements | P281 |
Hazard Classifications【危险分类】 | Repr. 2 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 2 |