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Dipeptidyl Peptidase VII human
产品别名
Dipeptidyl Peptidase VII human
Quiescent cell proline dipeptidase
DPP7
基本信息
| Enzyme Commission (EC) Number【酶学委员会(EC)编号】 | 3.4.14.- |
| NACRES | NA.54 |
| Application【应用】 | Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymphocytes . DPP7 is used to study the regulation of cell quiescence . Like DPP4, DPP7 may be useful in diabetes and vascular disease research . |
| Biochem/physiol Actions【生化/生理作用】 | DPP7 is essential for maintaining lymphocytes and fibroblasts in G(0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53 . DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. |
| Physical properties【物理属性】 | Contains amino acids 29 to end with a C-terminal His tag, MW=89.1 kDa |
| Unit Definition【单位定义】 | One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25 deg ℃ |
| Physical form【外形】 | Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 130 mM NaCl, 0.05% Tween-20, 10% glycerol |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in Sf9 cells |
| form【形式】 | solution |
| Specific Activity | ≥1,500 units/μg protein ≥1500 units/μg protein |
| mol wt【分子量】 | 89.1 kDa |
| relevant disease(s)【相关疾病】 | diabetes; cardiovascular diseases |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
