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NF-κB SN50M, Cell-Permeable Inactive Control Peptide-Calbiochem
产品别名
NF-κB SN50M, Cell-Permeable Inactive Control Peptide-Calbiochem
(AAVALLPAVLLALLAPVQRNGQKLMP)
基本信息
Empirical Formula【经验(实验)分子式】 | C123H215N33O30S |
Molecular weight | 2668.29 |
General description【一般描述】 | An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys363 and Gly for Arg364 in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM. An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys363 for Asn and Arg364 for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM. |
Biochem/physiol Actions【生化/生理作用】 | Primary Target an inactive control for SN50 peptide Product does not compete with ATP. Reversible: no Cell permeable: no |
Warning【警告】 | Toxicity: Standard Handling (A) |
Sequence【序列】 | H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH |
Physical form【外形】 | Supplied as a trifluoroacetate salt. |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions. |
Other Notes【其他说明】 | Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255. |
Legal Information【法律信息】 | Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee. CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (HPLC) |
form【形式】 | lyophilized |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) |
solubility【溶解性】 | water: 5 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 500 μg in Plastic ampoule Yes |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |