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Antipain, Dihydrochloride-CAS 37682-72-7-Calbiochem
产品编号: | 4091023 |
规格: | Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. |
CAS NO: | 37682-72-7 |
包装规格: | 10 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4091023 | 10 MG | 1940 |
产品别名
37682-72-7
Antipain, Dihydrochloride-CAS 37682-72-7-Calbiochem
基本信息
Empirical Formula【经验(实验)分子式】 | C27H44N10O6 · 2HCl |
Molecular weight | 677.62 |
MDL number | MFCD00135957 |
General description【一般描述】 | Effective concentration: 1-100 µM. A reversible protease inhibitor produced by actinomycetes. Inhibits cathepsin A and B as well as papain, and trypsin-like serine proteases. Acts by forming a hemiacetal adduct between the aldehyde group of the inhibitor and the active proteinase. Effective at concentrations range from 1 to 100 µM. Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC50 = 300 µM). |
Biochem/physiol Actions【生化/生理作用】 | Target IC50: 300 µM against trypsin-like serine proteases, papain and some cysteine proteases; Effective concentration: 1-100 µM Product does not compete with ATP. Cell permeable: no Reversible: yes Primary Target trypsin-like serine proteases, papain, and some cysteine proteases |
Warning【警告】 | Toxicity: Standard Handling (A) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C. |
Other Notes【其他说明】 | Lyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23. Ichikawa, S., et al. 1985. J. Reprod. Fertil.73, 385 Umezawa, H. 1976. Methods Enzymol.55, 678. Suda, H., et al. 1972. J. Antibiot. (Tokyo) 25, 263. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (HPLC) |
form【形式】 | powder |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
color【颜色】 | white |
solubility【溶解性】 | water: 1 mg/mL DMSO: 5 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C27H44N10O6.2ClH/c1-16(2)21(34-18(15-38)10-6-12-32-25(28)29)23(40)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17;;/h3-5,8-9,15-16,18-21,34H,6-7,10-14H2,1-2H3,(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43)(H,37,39,40);2*1H/t18?,19-,20?,21-;;/m0../s1 |
InChI key | GXQPAKIVOCLCHD-BXLPLHKWSA-N |
packaging【包装】 | 10 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |