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Anti-Cytokeratin 14 Antibody, clone RCK107
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8, The individual cytokeratin polypeptides are designated 1-20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. |
Specificity【特异性】 | Cytokeratin 14. MAB3232 reacts with basal cell compartments of stratified and combined epithelia.Reacts with cytokeratin 14, expressed in the basal cells of the larynx, esophagus, trachea, bladder, prostate, cervix, vagina, breast acini, skin and sweat glands. |
Immunogen【免疫原】 | Cytoskeletal preparation of TR146 epithelial cells. |
Application【应用】 | Western blot Immunohistochemistry on frozen tissue sections. Immunocytochemistry Flow cytometry Optimal working dilutions must be determined by the end user. Research Category Cell Structure Research Sub Category Cytokeratins Detect Cytokeratin 14 using this Anti-Cytokeratin 14 Antibody, clone RCK107 validated for use in FC, WB, IC, IH. |
Physical form【外形】 | Liquid in buffer with 0.1% sodium azide. Format: Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | RCK107, monoclonal |
species reactivity | human, canine, pig, rat |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG3 |
NCBI accession no.【NCBI登记号】 | NM_000526.3 |
UniProt accession no.【UniProt登记号】 | P02533 |
shipped in【运输】 | dry ice |
产品说明
Storage and Stability【储存及稳定性】 | Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |