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Anti-UTX Antibody
| 产品编号： | 4090954 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-UTX Antibody
Lysine-specific demethylase 6A, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone demethylase UTX is also known as Lysine-specific demethylase 6A, Ubiquitously-transcribed TPR protein on the X chromosome, and Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein. UTX is a histone demethylase that specifically demethylates trimethylated and dimethylated but not monomethylated histone H3 ′Lys-27′. UTX is involved in regulation of posterior development, and defects can cause Kabuki syndrome type 2 (KABUK2) |
| Specificity【特异性】 | Other homologies: Canine (99% sequence homology) and Bovine (96% sequence homology). |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human UTX. |
| Application【应用】 | Detect Histone demethylase UTX using this rabbit polyclonal antibody, Anti-UTX Antibody validated for use in western blotting & ICC. Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected UTX in HeLa, A431, and 3T3 cells. Research Category Epigenetics & Nuclear Function Research Sub Category Chromatin Biology |
| Quality【质量】 | Evaluated by Western Blotting in HeLa nuclear extract. Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTX in 10 µg of HeLa nuclear extract. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control HeLa nuclear extract |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, mouse |
| species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology) |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_066963 |
| UniProt accession no.【UniProt登记号】 | O15550 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... KDM6A(7403) |
产品说明
| Target description【目标描述】 | ~154 kDa observed. Uncharacterized band(s) may appear in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
