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Anti-IGF2 mRNA-binding protein 3 Antibody
产品编号: | 4088631 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μg |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-IGF2 mRNA-binding protein 3 Antibody
IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, insulin-like growth factor 2 mRN
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor 2 leader 3 mRNA and may repress translation of insulin-like growth factor 2 during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq]. |
Specificity【特异性】 | This antibody recognizes IGF2 mRNA-binding protein 3 at the C-terminus. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human IGF2 mRNA-binding protein 3 at and around the C-terminus. Epitope: C-terminus |
Application【应用】 | This Anti-IGF2 mRNA-binding protein 3 Antibody is validated for use in WB for the detection of IGF2 mRNA-binding protein 3. Research Sub Category Growth Factors & Receptors Research Category Apoptosis & Cancer Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate. Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP. |
Quality【质量】 | Evaluated by Western Blot in Hek293 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate. |
Physical form【外形】 | Affinity purified Purified rabbit serum in PBS with 0.09% azide. |
Analysis Note【分析说明】 | Control Hek293 cell lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | canine, human, mouse |
species reactivity (predicted by homology) | horse (based on 100% sequence homology), rhesus monkey (based on 100% sequence homology), dog (based on 100% sequence homology), chimpanzee (based on 100% sequence homology) |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_006538 |
UniProt accession no.【UniProt登记号】 | O00425 |
shipped in【运输】 | wet ice |
Gene Information | human ... IGF2BP3(10643) |
产品说明
Target description【目标描述】 | 64 kDa was observed. Predicted to cross-react with all the Isoforms of IGF2BP3. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |