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Anti-Pin1 Antibody

产品编号:4088529
规格:Upstate®, from rabbit
包装规格:100 μg
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4088529100 μg5520
基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Pin1 is a peptidyl-prolyl isomerase (PPI) that targets phosphorylated Ser or Thr residues followed by a Pro (S/T-P). Isomerization of phosphorylated Ser or Thr residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers, and has been shown to modify numerous proteins including p53,
NF-κB, c-Jun, cyclin D1, and β-catenin.
Specificity【特异性】
Pin1
Immunogen【免疫原】
Full-length His tagged human Pin-1
Application【应用】
Research Sub Category
Cell Cycle, DNA Replication & Repair
Research Category
Epigenetics & Nuclear Function
Anti-Pin1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of Pin1 & has been validated in IP & WB.
Quality【质量】
Routinely evaluated by immunoblot on RIPA lysates from mouse 3T3/A31 cells
Physical form【外形】
Protein A chromatography
Format: Purified
Presentation: 100 µg of protein A purified rabbit IgG in 100 µL of 0.014 M phosphate buffer, pH 7.6, 0.175 M NaCl, 0.07% Sodium Azide and 30% glycerol. Liquid at -20°C.
Analysis Note【分析说明】
Control
3T3 cell lysate, HeLa cell lysate, MCF-7 cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information【法律信息】
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype【同位素/亚型】
IgG
NCBI accession no.【NCBI登记号】
NM_006221
UniProt accession no.【UniProt登记号】
Q13526
shipped in【运输】
wet ice
Gene Information
human ... UBL5(59286)
产品说明
Target description【目标描述】
18kDa
Storage and Stability【储存及稳定性】
2 years at -20°C
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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