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Anti-CYP24A1 Antibody
| 产品编号： | 4087439 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CYP24A1 Antibody
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Also known as Vitamin D(3) 24-hydroxylase, CYP24A1 is a member of the cytochrome P450 (CYP) family of enzymes. Most members of the CYP family can metabolize multiple substrates, and can catalyze multiple reactions. The CYP24A1 is a mitochondrial protein that starts the breakdown of 1,25-dihydrozyvitamin D3 by hydroxylation of the side chain to form calcitroic acid. This enzyme also has a role in calcium homeostasis and the vitamin D endocrine system. |
| Specificity【特异性】 | Other Homologies: Bovine (92% sequence homology) and Rat (75% sequence homology). |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human CYP24A1. |
| Application【应用】 | Research Category Neuroscience Anti-CYP24A1 Antibody is an antibody against CYP24A1 for use in 0. Research Sub Category Developmental Signaling |
| Quality【质量】 | Evaluated by Western Blot in A549 cell lysate. Western Blot Analysis: 0.2 µg/mL of this antibody detected CYP24A1 in 10 µg of A549 cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control A549 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000773 |
| UniProt accession no.【UniProt登记号】 | Q07973 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~60 kDa observed. Two isoforms are known to exist at 59 kDa and 51 kDa This antibody is expected to recognize both isoforms. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
