KT5823-CAS 126643-37-6-Calbiochem

C₂₉H₂₅N₃O₅

495.53

MFCD09878278

Highly specific cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (K_i = 234 nM). Inhibits protein kinase C (K_i = 4.0 µM) and protein kinase A (K_i >10.0 µM) at higher concentrations.
Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (K_i = 234 nM).

Cell permeable: yes
Primary Target
PKG
Product competes with ATP.
Reversible: yes
Target K_i: 234 nM against protein kinase G

Toxicity: Standard Handling (A)

Further dilute with aqueous buffers just prior to use.

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Grider, J.R. 1993. Am. J. Physiol.264, G334.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥98% (HPLC)

solid

Calbiochem^®

OK to freeze
protect from light

white

DMSO: 1 mg/mL
DMF: soluble

ambient

−20℃

1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3/t20-,28+,29+/m1/s1

QTYMDECKVKSGSM-YMUMJAELSA-N

50, 100 μg in Plastic ampoule

11 - Combustible Solids

WGK 3