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Pitavastatin calcium

产品编号:4086966
规格:≥98% (HPLC)
CAS NO:147526-32-7
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40869665 MG729
408696625 MG2260
产品别名

147526-32-7

Pitavastatin calcium

(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt

(+)monocalcium bis{(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5dihydroxy-6-heptenoate}

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C25H23FNO4 · 0.5Ca
Molecular weight
440.49
Biochem/physiol Actions【生化/生理作用】
Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
optical activity【旋光性】
[α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1)
storage condition【储存条件】
desiccated
color【颜色】
white to beige
solubility【溶解性】
DMSO: 2 mg/mL, clear
storage temp.【储存温度】
2-8℃
InChI
1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
InChI key
RHGYHLPFVJEAOC-FFNUKLMVSA-L
安全信息
Pictograms【象形图】
GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H361f
Precautionary Statements
P201 - P308 + P313
Hazard Classifications【危险分类】
Repr. 2
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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