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Pitavastatin calcium
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086966 | 5 MG | 729 | |||
4086966 | 25 MG | 2260 |
产品别名
147526-32-7
Pitavastatin calcium
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt
(+)monocalcium bis{(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5dihydroxy-6-heptenoate}
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C25H23FNO4 · 0.5Ca |
Molecular weight | 440.49 |
Biochem/physiol Actions【生化/生理作用】 | Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
optical activity【旋光性】 | [α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1) |
storage condition【储存条件】 | desiccated |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1 |
InChI key | RHGYHLPFVJEAOC-FFNUKLMVSA-L |
安全信息
Pictograms【象形图】 | GHS08 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H361f |
Precautionary Statements | P201 - P308 + P313 |
Hazard Classifications【危险分类】 | Repr. 2 |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |