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HU-308
产品别名
256934-39-1
HU-308
HU308
(1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C27H42O3 |
Molecular weight | 414.62 |
MDL number | MFCD23102377 |
Biochem/physiol Actions【生化/生理作用】 | HU-308 is a potent, selective agonist of the cannabinoid receptor CB2. The Ki values for CB2 vs. CB1 are 22.7nM and >10 mM, respectively. HU-308 has anti-inflammatory and neuroprotective properties, and reduces liver damage in a hepatic ischemia/reperfusion injury model. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
optical activity【旋光性】 | [α]/D 180.0 to 130.0°, c = 0.5 in chloroform-d |
storage condition【储存条件】 | desiccated |
color【颜色】 | white to dark beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
SMILES string | CCCCCCC(C)(C1=CC(OC)=C(C(OC)=C1)[C@]2(C=C([C@@H]3C(C)([C@H]2C3)C)CO)[H])C |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |