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FM-479
产品别名
FM-479
2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide
(E)-2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide
FM-381 Inactive Control
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H26N6O2 |
| Molecular weight | 442.51 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | FM-479 is an FM-381 structural analog that exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range of 100-300 nM. For characterization details of the active probe, FM-381, please visit the FM-381 probe summary on the Structural Genomics Consortium (SGC) website. FM-381, the active probe, is available from Sigma. To learn more about and purchase FM-381, click here. To learn about other SGC chemical probes, visit sigma.com/sgc |
| Features and Benefits【特点和优势】 | FM-479 is a negative control for FM-381, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | yellow to orange |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN(C(/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(N(C)C=C4)C4=C3N2C5CCCCC5)=O)C |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
