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N6-(4-Hydroxybenzyl) adenine riboside
产品别名
110505-75-4
N6-(4-Hydroxybenzyl) adenine riboside
NHBA
N6-(4-Hydroxybenzyl)-adenosine
N-[(4-Hydroxyphenyl)methyl]adenosine
T1-11
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H19N5O5 |
| Molecular weight | 373.36 |
| MDL number | MFCD18641957 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | N6-(4-Hydroxybenzyl) adenine riboside (NHBA) is an orally available and brain penetrant active active ingredient of Gastrodia elata rhizomes used for the treatment of insomnia. N6-(4-Hydroxybenzyl) adenine riboside is an adenosine A2A receptor and the equilibrative nucleoside transporter 1 (ENT1) agonist. It exhibits sedative and hypnotic effects by binding to adenosine A1 and A2A receptors in mice. N6-(4-Hydroxybenzyl) adenine riboside exerted a therapeutic effect on HD transgenic mouse by decreasing protein level of polyglutamine-expanded huntingtin in the striatum. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC[C@H]1O[C@@H](N2C=NC3=C2N=CN=C3NCC4=CC=C(O)C=C4)[C@H](O)[C@@H]1O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
