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IC87201
产品别名
866927-10-8
IC87201
2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol
2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichloro-phenol
Phenol, 2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro-
IC 87201
IC-87201
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H10Cl2N4O |
| Molecular weight | 309.15 |
| Biochem/physiol Actions【生化/生理作用】 | IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to NMDA receptor antagonists nNOS/PSD-95 protein-protein interaction inhibitors spared source memory, spatial memory, and motor function in rats. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to brown |
| solubility【溶解性】 | DMSO: 5 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
