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G6PDi-1
产品别名
2457232-14-1
G6PDi-1
4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C14H12N4OS |
Molecular weight | 284.34 |
MDL number | MFCD32899271 |
Biochem/physiol Actions【生化/生理作用】 | G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1 |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |