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E7820
产品别名
289483-69-8
E7820
E 7820
3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
3-Cyano-N-(3-cyano-4-methyl-1H-indole-7-yl)benzensulfonamide
NSC 719239
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H12N4O2S |
| Molecular weight | 336.37 |
| MDL number | MFCD09833234 |
| Biochem/physiol Actions【生化/生理作用】 | E7820 (NSC 719239) is an orally available anticancer and antiangiogenic agent that inhibits VEGF-2 or FGF-2-induced tube formation of HUVEC cells through the suppression of integrin α2. E7820 promotes selective proteasomal degradation of the U2AF-related splicing factor CAPERα (coactivator of activating protein-1 and estrogen receptors) by ubiquitination and degradation via CRL4DCAF15. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
