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17:0(2R-OH) Ceramide
产品编号: | 4085020 |
规格: | N-(2′-(R)-hydroxyheptadecanoyl)-D-erythro-sphingosine, powder |
CAS NO: | 1246298-46-3 |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品别名
1246298-46-3
17:0(2R-OH) Ceramide
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C35H69NO4 |
Molecular weight | 567.93 |
NACRES | NA.25 |
General description【一般描述】 | 17:0(2R-OH) Ceramide is a 2R hydroxylated heptadecanoic acid-containing sphingolipid. It is present mainly in epidermis. |
Biochem/physiol Actions【生化/生理作用】 | Hydroxy fatty acids (hFA)-sphingolipids play a vital role in cell signaling. They also help in cell differentiation and apoptosis. hFA-ceramides are involved in the formation of the epidermal barrier. Fatty acid 2-hydroxylases (FA2H) synthesize hFA-ceramides. Mutations of FA2H have been linked to neurological disorders like spastic paraparesis in humans and leukodystrophy. hFA-ceramides in the cell membrane play a crucial role in imparting the PM02734 drug with anti-tumor activity. |
产品性质
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 860817P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCC)=O)CO |
packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860817P-5mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |