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12:0(2R-OH) Ceramide
| 产品编号： | 4084519 |
| 规格： | N-(2′-(R)-hydroxylauroyl)-D-erythro-sphingosine, powder |
| CAS NO： | 1246298-44-1 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1246298-44-1
12:0(2R-OH) Ceramide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C30H59NO4 |
| Molecular weight | 497.79 |
| NACRES | NA.25 |
| General description【一般描述】 | Ceramides containing 2-hydroxy fatty acid (hFA) are found primarily in the epidermis. 12:0(2R-OH) Ceramide is a 2R hydroxylated lauric acid-containing ceramide. |
| Biochem/physiol Actions【生化/生理作用】 | Hydroxy fatty acid (hFA)-sphingolipids play a specific role in cell signaling. Synthesis of hFA-ceramides requires fatty acid 2-hydroxylase (FA2H). Mutations of this key enzyme are associated with the development of nervous system disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for the epidermal permeability barrier function. The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860811P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCC)=O)CO |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860811P-5mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
