Necrostatin-1, Inactive Control-CAS 64419-92-7-Calbiochem

C₁₂H₁₁N₃OS

245.30

A cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control.

Note: This inactive inhibitor of necrosis should not be used in high concentration.
A cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control.



Note: This inactive inhibitor of necrosis should not be used in high concentration.

Cell permeable: yes
Primary Target
Inactive control for Nec-1 (Cat. No. 480065)
Product does not compete with ATP.
Reversible: no

Toxicity: Standard Handling (A)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Takahashi et al. 2012. Cell Death and Disease3, e437.
Degterev, A., et al. 2005. Nat. Chem. Biol.1, 112.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (HPLC)

crystalline solid

Calbiochem^®

OK to freeze
protect from light

light yellow

DMSO: 10 mg/mL
methanol: 5 mg/mL

ambient

2-8℃

5 mg in Plastic ampoule
Packaged under inert gas

11 - Combustible Solids

WGK 1