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cFMS Receptor Inhibitor IV-CAS 959626-45-0-Calbiochem
产品编号: | 4083817 |
规格: | The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
CAS NO: | 959626-45-0 |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
959626-45-0
cFMS Receptor Inhibitor IV-CAS 959626-45-0-Calbiochem
5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV
基本信息
Empirical Formula【经验(实验)分子式】 | C22H26N4O2 |
Molecular weight | 378.47 |
General description【一般描述】 | A cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM). |
Warning【警告】 | Toxicity: Standard Handling (A) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
Other Notes【其他说明】 | Patch, R.J., et al. 2007. Bioorg. Med. Chem. Lett.17, 6070. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | yellow |
solubility【溶解性】 | DMSO: 5 mg/mL |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mg in Glass bottle Packaged under inert gas |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 2 |