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Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor® 488 conjugate
产品编号: | 4082410 |
规格: | clone 6C1.2, from mouse, ALEXA FLUOR® 488 |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor® 488 conjugate
Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells. |
Immunogen【免疫原】 | recombinant protein corresponding to mouse DPPA-2. |
Application【应用】 | This Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of DPPA-2. Research Sub Category Pluripotent & Early Differentiation Research Category Stem Cell Research |
Quality【质量】 | Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012). |
Physical form【外形】 | Purified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
Analysis Note【分析说明】 | Control Mouse Embryonic Stem Cells (SCR012). |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | ALEXA FLUOR is a registered trademark of Life Technologies |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | ALEXA FLUOR® 488 |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 6C1.2, monoclonal |
species reactivity | mouse |
technique(s) | immunocytochemistry: suitable |
NCBI accession no.【NCBI登记号】 | NP_082891 |
UniProt accession no.【UniProt登记号】 | Q9CWH0 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~30 kDa observed |
Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |