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Microbial DNA standard from Bacillus subtilis
产品编号: | 4080030 |
规格: | Suitable for PCR, Sequencing and NGS, 10 ng/μL |
包装规格: | 0.3 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品性质
form【形式】 | liquid |
concentration【浓度】 | 10 ng/μL |
technique(s) | PCR: suitable |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
基本信息
General description【一般描述】 | Microbial DNA standard from Bacillus subtilis (B. subtilis) is a genomic DNA microbial standard that can serve as a standard for benchmarking the performance, along the workflow of microbiomics or meta-genomics analyses. It can also be used as a tool to increase reproducibility and allow comparison of results obtained by different labs. Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses. Bacillus subtilis is a gram positive, aerobic bacterium, rod-shaped, endospore-forming, catalase-positive. It is traditionally considered as a soil microorganism. Bacillus subtilis is genetically well characterized and serves as a model organism for important gram-positive pathogens such as Bacillus anthracis, Staphylococcus aureus etc. B. subtilis possess an extreme adaptation ability to various environmental stress conditions by modifying its motility, uptake of exogenous DNA, biofilm formation and sporulation. Recent studies have identified and characterized B. subtilis isolates from human gastrointestinal track suggesting B. subtilis as a gut commensal. Moreover, B. subtilis presence in the gut was found to correlate with probiotic effects such as anti-diarrhea effect, anti-microbial effect, immune-stimulatory effect, competition with pathogens, normal flora growth stimulation and prevention of intestinal inflammation. B. subtilis beneficial effect on gut inflammation may also suggest it as potential probiotic treatment for inflammatory bowel diseases (IBD), including Crohn′s and ulcerative colitis. In addition, it was demonstrated that a peptide produced by B. subtilis possess antiviral effect against influenza virus. |
Application【应用】 | Suitable for Quantitative standard for PCR, Sequencing and NGS |
Features and Benefits【特点和优势】 |
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Physical form【外形】 | Liquid - The genomic DNA is provided at >=10 ng/μL concentration in TE buffer pH 8.0 |
Other Notes【其他说明】 | It is recommended to avoid freeze thaw cycles of this product. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |