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PPACK, Dihydrochloride-CAS 142036-63-3-Calbiochem
| 产品编号： | 4078622 |
| 规格： | PPACK, Dihydrochloride, CAS 142036-63-3, is an extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. |
| CAS NO： | 142036-63-3 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
142036-63-3
PPACK, Dihydrochloride-CAS 142036-63-3-Calbiochem
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H33Cl3N6O3 |
| Molecular weight | 523.88 |
| General description【一般描述】 | Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator. Factor VIIa, and Factor XIa. Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator, Factor VIIa, and Factor XIa. Also available as a 25 mM solution in H2O (Cat. No. 508773). |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Primary Target Thrombin Reversible: no Kobs/[I] = 107 M⁻¹ sec⁻¹ as inhibitor of thrombin Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | H-D-Phe-Pro-Arg-chloromethylketone, 2HCl |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions (pH <4) are stable for up to 4 months at -20°C. Rapidly decomposes at an alkaline pH. |
| Other Notes【其他说明】 | Rosado, J. A., et al. 2002. J. Biol. Chem.277, 42157. Odake S., et al. 1995. J. Enzyme Inhib.9, 17. Arni, R.K., et al. 1993. Biochemistry 32, 4727. Yamashita, T., et al. 1993. Thromb. Res. 69, 93. Schmaier, A.H., et al. 1992. Thromb. Res.67, 479. Collen, D., et al. 1982. J. Lab. Clin. Med.99, 76. Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826. Kettner, C., and Shaw, E. 1979. Thromb. Res.14, 969. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥80% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | water: 100 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
