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Caspase-3 Substrate VII, Fluorogenic-Calbiochem
产品别名
Caspase-3 Substrate VII, Fluorogenic-Calbiochem
Ac-DEVD-AFC
基本信息
Empirical Formula【经验(实验)分子式】 | C30H34F3N5O13 |
Molecular weight | 729.61 |
General description【一般描述】 | Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10. Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10. |
Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Cell permeable: no Primary Target Fluorogenic caspase-3 substrate |
Warning【警告】 | Toxicity: Standard Handling (A) |
Sequence【序列】 | Ac-Asp-Glu-Val-Asp-AFC |
Reconstitution【重悬】 | Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
Other Notes【其他说明】 | Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | lyophilized solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated protect from light |
color【颜色】 | white |
solubility【溶解性】 | DMSO: 5 mg/mL |
fluorescence【荧光】 | λex ~400 nm λem ~505 nm |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 1, 5 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |