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Andrastin A
产品别名
174232-42-9
Andrastin A
(3β,5β,8α,9β,10α,13α)-3β-(acetyloxy)-4,4,8,12,16-pentamethyl-15,17,19-trioxoandrost-11-ene-14-carboxylic acid methyl ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C28H38O7 |
| Molecular weight | 486.60 |
| MDL number | MFCD28898503 |
| Biochem/physiol Actions【生化/生理作用】 | Andrastin A is a meroterpenoid protein farnesyltransferase inhibitor with anticancer activity. It has been shown to inhibit the farnesyltransferase activity of the oncogenic Ras proteins and inhibit the efflux of anticancer drugs from multidrug-resistant cancer cells. Farnesyltransferase inhibitor with anticancer activity; mycotoxin |
产品性质
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3/t16?,18?,19-,20?,25?,26+,27+,28?/m0/s1 |
| InChI key | GRBXNADBNJGZRK-BCMOVVIDSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
