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AS-252424
产品别名
900515-16-4
AS-252424
5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H8FNO4S |
| Molecular weight | 305.28 |
| MDL number | MFCD11045281 |
| PubChem Substance ID【PubChem化学物质编号】 | 329771025 |
| Biochem/physiol Actions【生化/生理作用】 | AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor with IC50 = 30 nM in a mouse model. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Oc1cc(F)ccc1-c2ccc(\C=C3\SC(=O)NC3=O)o2 |
| InChI | 1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6+ |
| InChI key | OYYVWNDMOQPMGE-WUXMJOGZSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
