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Arylquin 1
产品别名
1630743-73-5
Arylquin 1
3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H16FN3 |
| Molecular weight | 281.33 |
| MDL number | MFCD28580129 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825755 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | , white to yellow to light brown |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F |
| InChI | 1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20) |
| InChI key | RHAQINSYYSNKKI-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
