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Anti-ZAP70 (Ab-493) antibody produced in rabbit
产品别名
Anti-ZAP70 (Ab-493) antibody produced in rabbit
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Anti-SRK antibody produced in rabbit
Anti-zeta-chain (TCR) associated protein kinase 70kDa antibody produced in rabbit
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Peptide sequence around aa. 491-495 (S-Y-Y-T-A), according to the protein ZAP70. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | ~70 kDa |
species reactivity | mouse, human, rat |
concentration【浓度】 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
isotype【同位素/亚型】 | IgG |
immunogen sequence【免疫原序列】 | (S-Y-Y-T-A) |
NCBI accession no.【NCBI登记号】 | NP_001070.2 |
UniProt accession no.【UniProt登记号】 | P43403 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... ZAP70(7535) |
产品说明
Target description【目标描述】 | ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the zeta chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-zeta chain, which can mediate the transduction of extracellular stimuli into cellular effector functions. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |