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Anti-TRPM5 (AB1) antibody produced in rabbit
产品别名
Anti-TRPM5 (AB1) antibody produced in rabbit
Anti-LTRPC5
Anti-MTR1
Anti-Transient receptor potential cation channel, subfamily M, member 5
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | TRPM5 is a Ca+-activated channel that is involved in the transduction of umami, sweet and bitter tastes. Voltage, temperature, acidic pH and phosphoinositides are known to modulate TRPM5 function. It regulates mucin secretion in colon and pheromone transduction in olfactory epithelia. TRPM5 has been studied as a target for obesity treatment. Rabbit Anti-TRPM5 antibody recognizes human, canine, and mouse TRPM5. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human TRPM5 |
| Application【应用】 | Rabbit Anti-TRPM5 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | TRPM5 is a voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. It is activated by arachidonic acid in vitro. It may be involved in perception of bitter, sweet and umami tastes. It may also be involved in sensing semiochemicals. |
| Sequence【序列】 | Synthetic peptide located within the following region: EKHISEQRAGYGGTGSIEIPVLCLLVNGDPNTLERISRAVEQAAPWLILV |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 131 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_055370 |
| UniProt accession no.【UniProt登记号】 | Q9NZQ8 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TRPM5(29850) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
