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Anti-TAF15 antibody produced in rabbit

产品编号:3399354
规格:IgG fraction of antiserum
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3399354100 μL3310
产品别名

Anti-TAF15 antibody produced in rabbit

Anti-TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa

基本信息
NACRES
NA.41
General description【一般描述】
TAF15 is known to regulate cell growth and cell cycle genes through miRNAs. Rabbit Anti-TAF15 antibody recognizes human, mouse, rat, bovine, and chicken TAF15.
Immunogen【免疫原】
Synthetic peptide directed towards the N terminal region of human TAF15
Application【应用】
Rabbit Anti-TAF15 antibody can be used for western blotting (3.0μg/ml) assays.
Biochem/physiol Actions【生化/生理作用】
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF15 encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas.
Sequence【序列】
Synthetic peptide located within the following region: GGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSD
Physical form【外形】
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
IgG fraction of antiserum
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
62 kDa
species reactivity
human
concentration【浓度】
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_003478
UniProt accession no.【UniProt登记号】
Q92804
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... TAF15(8148)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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